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gamma-Hydroxybutyric acid or γ-Hydroxybutyric acid (GHB), often called four-hydroxybutanoic acid, can be a Obviously taking place neurotransmitter as well as a psychoactive drug. It is a precursor to GABA, glutamate, and glycine in certain brain locations. It functions around the GHB receptor and is particularly a weak agonist with the GABAB receptor. GHB continues to be use during the health care setting being a general anesthetic and being a treatment for read more cataplexy, narcolepsy, and alcoholism.It is additionally use illegally being an intoxicant, being an athletic efficiency enhancer, to be a date rape drug, and like a leisure drug.

It is usually use in the shape of the salt, like sodium γ-hydroxybutyrate (NaGHB, sodium oxybate, or Xyrem) or potassium γ-hydroxybutyrate (KGHB, potassium oxybate). GHB is likewise produce as a result of fermentation, and is use in smaller portions in certain beers and wines, beef and small citrus fruits.

Succinic semialdehyde dehydrogenase deficiency is actually a ailment that triggers GHB to build up from the blood.

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